A Phase 2, Double-Masked, Placebo-Controlled, Dose Range Finding Study of Danicopan (ALXN2040) in Patients with Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD).

A Phase 2, Randomized, Placebo-Controlled, Double Masked Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRX, an Antisense Inhibitor of Complement Factor B, in Patients with Geographic Atrophy Secondary to Age-Related Macular Degeneration.

A Decentralized Epidemiological Study of the Progression of Age-Related Macular Degeneration.

A Phase 3 Multicenter, Randomized, Double-Masked, Sham Controlled Clinical Trial to Assess the Safety and Efficacy of Intravitreal Administration of Zimura (Complement C5 Inhibitor) In Patients with Geographic Atrophy secondary to Age-Related Macular Degeneration.

A Phase 2b Randomized, Double-Masked, Controlled Trial to Assess the Safety and Efficacy of Intravitreous Administration of Zimura (Anti-C5 Aptamer) in Subjects with Geographic Atrophy secondary to Dry Age-Related Macular Degeneration.

A Phase II, Open-Label, Outcomes-Assessor Masked, Multicenter, Randomized, Controlled Study to Evaluate the Safety and Efficacy of Two Doses of GT005 Administered as a single subretinal Injection in Subjects with Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration.

A Study to Genetically Define Subjects with Geographic Atrophy Secondary to Age-Related Macular Degeneration.

A Phase 3, Multicentre, Double-masked, Randomised Study to Evaluate the Efficacy and Safety of Intravitreal OPT-302 in Combination with Aflibercept, Compared with Aflibercept Alone, in Participants with Neovascular Age-related Macular Degeneration (nAMD) (Aspire)

A Randomized, Partially-Masked, Controlled, Phase 2b/3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants with nAMD.

A Randomized, Partially Masked Controlled, Phase 3 Clinical Study to Evaluate the Efficacy and Safety of RGX-314 Gene Therapy in Participants with nAMD.

A Multicenter, Double Masked, Randomized, Dose-Ranging Trial to Evaluate the Efficacy And Safety of Conbercept Intravitreal Injection in Subjects with Neovascular Age-related Macular Degeneration.

A Phase III, Multicenter, Randomized, Double-Masked, Active Comparator-Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients with Neovascular Age-Related Macular Degeneration.

A Clinical Effectiveness, Multicenter, Randomized, Double-Masked, Controlled Study of the Efficacy and Safety of ONE-5010 in Subjects with Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration.

A Phase III Study of the Efficacy and Safety of Squalamine Lactate Ophthalmic Solution 0.2%, Twice Daily in Subjects with Neovascular Age-Related Macular Degeneration.

A Phase 2, Prospective, Multicenter, Randomized, Double-Masked, Active Controlled Study To Assess the Safety, Tolerability, and Evidence of Activity of a Repeat Intravitreal Injection of UBX1325 In Patients with Neovascular Age-Related Macular Degeneration.

A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Patients with Neovascular Age-Related Macular Degeneration.

A Phase 2b, Prospective, Multicenter, Randomized, Double-Masked, Active-Controlled Study to Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients with Diabetic Macular Edema (Aspire).

A Phase IV, Multicenter, Open Label, Single Arm Study to Investigate Faricimab (RO6867461) Treatment Response in Treatment Naïve, Underrepresented Patients with Diabetic Macular Edema.

A Phase III, Multicenter, Randomized Study of the Efficacy, Safety and Pharmacokinetics Of the Port Delivery System with Ranibizumab in Patients with Diabetic Retinopathy.

A Phase 2, randomised, multicentre study to assess the dose level of multiple THR-149 injections and to evaluate the efficacy and safety of THR-149 versus aflibercept for the treatment of diabetic macular oedema (DME).

Randomized Trial of Intravitreous Aflibercept versus Intravitreous Bevacizumab + Deferred Aflibercept for Treatment of Central-Involved Diabetic Macular Edema.

A 12-month, 2-arm, Randomized, Double-Masked, Multicenter Phase III Study Assessing the Efficacy and Safety of Brolucizumab every 4 weeks versus Aflibercept every 4 weeks in Adult Patients with Visual Impairment due to Diabetic Macular Edema.

A Phase III, Multicenter, Randomized, Double-Masked, Active-comparator Controlled Study to Evaluate the Efficacy and Safety of Faricimab in Patients with Diabetic Macular Edema.

A Randomized, Placebo-Controlled, Double-Masked Study of the Safety and Efficacy of Orally Administered APX3330 in Subjects with Moderately Severe to Severe Non-Proliferative Diabetic Retinopathy or Mild Proliferative Diabetic Retinopathy.

A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Patients with Diabetic Macular Edema.

A Natural History Observation and Registry Study of Macular Telangiectasia Type 2.

A Phase III, Multicenter, Randomized, Sham-Controlled Study to Determine the Safety and Efficacy of Renexus in Macular Telangiectasia Type 2.

Enrollin A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects with Primary Indeterminate Lesions or Small Choroidal Melanoma.